Abstract: Palliative care includes range of illnesses involving “physical, psychosocial and emotional requirements of chronic ill patients”. The demand for palliative will continue to increase worldwide due to escalating burden of communicable/non-communicable infections and diseases and ageing populations. Adequate measures and “early palliative care” possibly limit unnecessary hospitalizations. Nurses are the primary and essential source for providing safe and efficient care globally. Efficient nurse practitioners “lowers the stress, suffering and complications of patients facing death”. Further, nurses extend “physical, social, psychological” assistance to patients with severe illnesses. Nurses have shown a proven commitment in the treatment of end-of-life patients with better outcomes to palliative care.